Low Dose Naltrexone Reduces In Vitro Endoplasmic Reticulum Stress and Stimulates Wound Healing in Intestinal Epithelial Cells (Abstract)

Low Dose Naltrexone Reduces In Vitro Endoplasmic Reticulum Stress and Stimulates Wound Healing in Intestinal Epithelial Cells

Journal of Crohn's and Colitis
March 2016
https://academic.oup.com/ecco-jcc/article/10/suppl_1/S136/2481649

Naltrexone (NTX), a μ-opioid receptor (MOR) antagonist, up regulates MOR and its ligands when used at low doses. It may have a beneficial effect in the treatment of IBD by directly stiumulating epithelial wound healing and reducing intestinal ER stress.