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LDN and MDD: A Case Study

Speaker

Beth Livengood NMD

Description: 

Major Depressive Disorder (MDD) affects 1 in 12 Americans and is commonly associated with chemical imbalances within the central nervous system. However, a neurotransmitter imbalance is not necessarily the only cause of depression; hence, antidepressants are not always the most suitable treatments. The following case suggests that MDD may involve inflammatory responses and demonstrates a significant reduction in MDD symptoms through therapeutic administration of Low Dose Naltrexone (LDN). LDN’s efficacy in this case was evident in treating a patient with a history of MDD for over 25 years with a resolution of symptoms in a few months. 

I. Why a primary care doctor might need to treat MDD or deal with suicidal patients

               A. The cycle of PAIN, ILLNESS, DEPRESSION

               B. Causes of depression

                              1. Inflammation (hence the use of LDN)

                              2. TBI

                              3. Circumstantial/ Constitution

                              4. Chronic pain or medical conditions

II. Recognizing MDD and Suicidal Ideation in your patients

               A. DSM 5 diagnostic criteria for MDD

               B. 5 Suicide Screening Questions

               C. Resources for suicidal patients

III. Case Study

               A. History

                              1. Possible causes of depression

                              2. Conventional medications used in this case over a 25 year period

               B. Diagnostic criteria and initial work-up findings

               C. Treatment Protocol

                              1. LDN dosing including taper protocol and timeline

                              2. Adjunct therapies used in this case

               D. Results and post-treatment work-up

IV. Alternative Therapies used safely with LDN

               A. Common comorbidities with depression

               B. Treatments for comorbidities known to be safe with LDN

               B. Contraindications with LDN

Learning Objectives:

RECOGNIZE MDD / SUICIDAL IDEATION IN YOUR PATIENTS

HAVE A PLAN TO HELP THEM

UNDERSTAND YOUR ROLE WITH PATIENTS WITH MDD

LEARN DOSING OPTIONS FOR LDN WITH MDD

CONSIDER ADJUNCT THERAPIES WITH LDN FOR MDD