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The latest research on Th17 and its role in autoimmunity


Debbie Hamilton, MD, MPH

Description: The old paradigm that immune balance is obtained by regulating T helper1 (Th1)and T helper 2 (Th2) cells has been challenged along with the idea that elevated Th1 is always associated with autoimmune disease. With the differentiation of T helper 17 (Th17) cells from Th1 cells came the realization that the immune system is much more complex than the Th1/Th2 paradigm. Decreasing autoimmunity and chronic infections involves balancing Th17 and Treg cells in addition to Th1 and Th2 cells.  Understanding the imbalanced immune cycle that is common in many of our chronic disease patients leads to new treatment modalities including transfer factors, natural anti-inflammatories, and LDN.

Session Learning Objective:  

  1. Understand the individual roles and interrelationship of the different T helper cells including Th1, Th2, Th17 and Treg cells
  2. Learn about the research on Th17 and its role in creating autoimmunity
  3. Learn how low Th1, elevated Th17, and elevated Th2 contribute to the cycle of chronic inflammation and autoimmunity
  4. Discuss how to use transfer factors, natural anti-inflammatories, and LDN to modulate and balance the immune system